How SPRi is Used

A SPRi experiment consists of 4 steps:

The Biochip is selected according to the ligands immobilized
The ligands are immobilized on the SPRi-Biochip surface in a matrix format
The sample solution is passed over the SPRi-Biochip surface and variations of reflectivity are recorded in real time
The kinetic data are analyzed to extract quantitative information and/or kinetic rate constants of the interactions.

Ligand immobilization on a flexible biochip in a microarray format.

Dedicated surface chemistries allow ligand immobilization on a flexible biochip in a microarray format.

After injection of the sample solution, several hundreds of different molecular interactions can be monitored in real time.

After injection of the sample solution, several hundreds of different molecular interactions can be monitored in real time.

SPR phenomenon occurs at the interface between the biochip metallic surface and the liquid medium.

SPR phenomenon occurs at the interface between the biochip metallic surface and the liquid medium.